It is possible for lower eyelid roll over with white granules to heal on its own, but some of them need to be recovered through treatment, which is related to the patient’s condition. Lower eyelid rolling open with white particles may be caused by a variety of reasons, such as conjunctival stones, lid gland cysts and so on. Conjunctival stone is the eyelid conjunctiva due to the shedding of cells and chronic inflammation, long-term condensation of small dots, rice-sized white or gray-white stones, increased volume can cause patients eye foreign body sensation, patients can be guided by the doctor to carry out the stone removal surgery, to alleviate the symptoms of eye discomfort. Blepharophalangeal cysts caused by obstruction of the blepharophalangeal glands can be treated with localized hot compresses on the eyes, which can soften the secretions inside the blepharophalangeal glands and encourage them to be discharged, thus allowing them to heal on their own. However, some patients are unable to heal themselves and require blepharocystectomy. It is recommended that patients with white granules on the eyelids seek prompt medical attention to evaluate their condition and follow the doctor’s instructions for treatment.