Loss of voice in the throat is mostly due to upper respiratory tract infections, vocal cord nodules, vocal cord polyps, laryngeal cancer and vocal cord paralysis caused by various reasons. For the upper respiratory tract infection caused by congestion and swelling of the mucous membrane of the throat, especially the vocal folds of congestion and swelling, resulting in vocal folds can not be closed or have gaps when vocal, hoarse voice or even loss of voice. Treatment is mainly active treatment of upper respiratory tract infection, abstinence from sound, can be nebulized treatment, etc. Generally about 5 days inflammation control, hoarseness will be effectively improved. For vocal cord nodules and vocal cord polyps, which are caused by too much talking and too loud, the main treatment is to surgically remove the vocal cord swelling to improve hoarseness. For hoarseness caused by laryngeal cancer, which is caused by cancer cells infiltrating the vocal folds, radiotherapy or surgery can be given, but the hoarseness will not improve or even worsen. Hoarseness caused by vocal cord paralysis is mostly due to the compression of the laryngeal nerve by cancerous tumors, which are mostly seen in esophageal cancer and mediastinal cancer, and the hoarseness can be improved after surgery to remove the cancerous tumors.