Granular sperm in the semen is mainly due to the lack of liquefaction of the semen. When this occurs, it indicates a physical abnormality, such as reproductive tract infections, such as prostatitis and vesiculitis. Since 70% of semen is made up of seminal vesicle and prostate fluid, when inflammation occurs in the seminal vesicle and prostate gland, it can cause semen to become indistinct. The prostate fluid itself is the main component of semen, while the seminal vesicle fluid is the seminal fluid released from the seminal vesicles, both of which have their own function of promoting the liquefaction of semen. When inflammation occurs in either the prostate gland or the seminal vesicles, it can cause changes in the composition of both fluids, thus affecting the liquefaction of semen, which can lead to crystallization and granulation of semen. It is important to seek medical attention in time to identify the cause of the problem and further treat it under the guidance of a doctor.