Spitting mucus of esophageal cancer is serious, mainly because after the tumor of esophageal cancer enlarges, the liquid secreted in the esophagus cannot flow into the stomach through the narrow part and is retained in the esophagus, so spitting mucus indicates that the lesion is further aggravated. Active treatment should be carried out, such as radiotherapy and chemotherapy, and further CT examination should be carried out to see whether the scope of the lesion has increased and whether the tumor has developed forward, and active treatment should be given. Spitting mucus of esophageal cancer indicates further aggravation of the lesion, which should be highly valued and actively treated.