Usually proteinuria is very difficult to see protein with the naked eye, usually need to improve the urinalysis examination to clarify the existence of proteinuria, but most proteinuria patients can be observed through the naked eye found that the urine foam increases, and is not easy to disappear and so on. The reason for the increase in proteinuria mainly includes physiological and pathological factors. 1. physiological: proteinuria is mainly manifested as increased urine foam, not easy to disappear, etc., can be caused by cold, high fever, strenuous exercise, cold, emotional excitement, and so on. When the cause is removed, proteinuria will disappear naturally and no medication is needed. 2. Pathological: proteinuria may cause generalized edema or facial edema, hypoproteinemia, etc., also foamy urine, usually caused by urinary tract infection, glomerulonephritis, nephrotic syndrome and other diseases, the urine can be cloudy, foam, tubular urine and other manifestations, it is recommended to take methylprednisolone, cyclosporine, tacrolimus and other drugs under the guidance of the doctor for treatment. It is recommended that patients with proteinuria go to the hospital in time, after clarifying the cause of the disease, under the guidance of the doctor’s reasonable standardization of diagnosis and treatment.