Pre-menopausal sexual desire at the age of fifty can be physiological or pathological. Physiological conditions can be left unintervened, while pathological conditions should be given different treatments according to different etiological factors, the common causes of which include endocrine disorders, ovarian tumors, and mental factors. 1. Physiological conditions: Due to individual differences, the age at which each person enters perimenopause is different. For late menopausal women, strong libido before menopause at the age of 50 is a normal physiological phenomenon, no need to intervene, besides, this age group is no longer worried about the concern of unwanted pregnancy, which is also one of the reasons for strong libido. 2. Pathologic conditions: (1) Endocrine disorders: such as hyperthyroidism, the use of large amounts of sex hormone drugs can cause increased libido, but this situation is a pathological phenomenon, need to be treated. (2) Ovarian tumor: ovarian tumors with the function of secreting sex hormones can also increase libido, so relevant auxiliary examinations should be carried out, such as abdominal ultrasound or magnetic resonance and sex hormone six and so on, to clarify the cause of the disease, and then give surgical treatment and so on. (3) Psychological factors: Some women with mania and schizophrenia may show increased libido, which is mainly related to the excitement of the libido center in the brain. In addition, taking antidepressants can also cause increased libido. There may be other reasons for pre-menopausal strong libido at the age of fifty. If strong libido is accompanied by other abnormalities, you should go to the hospital in time and do the relevant examinations to clarify the cause of the disease and guide the treatment, and do not take medication without authorization, so as not to cause delays in the condition, resulting in a bad outcome.