Always get pimples, belongs to acne, and androgen secretion exuberant, follicle duct hyperkeratosis, propionic acid acne bacillus reproduction and other factors related to, can be through the general treatment, topical drug therapy, systemic medication, physical therapy and other measures to regulate. 1. General treatment: keep the skin clean and hygienic, use water or suitable cleansing products to remove excess oil flakes on the surface of the skin, but avoid excessive cleaning, pay attention to oil control and moisturizing, keep the bowel movement smooth, and avoid staying up late. 2. Topical medication: Adapalene gel, vitamin A acid cream and other drugs can be used externally to dissolve keratin, but also with clindamycin ointment, fusidic acid cream and other antibiotic drugs. 3. Systemic medication: you can take minocycline, doxycycline and other antibiotics, or oral isotretinoin and other drugs to regulate sebum secretion and follicle keratinization, and in severe cases, you can cooperate with spironolactone anti-androgen therapy. 4. Physical therapy: LED blue light or red light irradiation is suitable for mild and moderate lesions, and photodynamic therapy is used for moderate to severe acne. It is recommended to go to the hospital for examination first, and the drugs need to be used under the guidance of the doctor.