Miso refers to misoprostol, abdominal pain after taking it is usually normal, if the pain is paroxysmal and no other discomfort, observation is recommended. However, if the pain is persistent and severe, it is an abnormal situation, and you should consult a doctor promptly. Misoprostol can make smooth muscle contraction, enhance intrauterine pressure, and at the same time allow the cervix to soften and discharge the products of pregnancy, so the symptoms of abdominal pain will occur. Most of the abdominal pain will be gradually reduced in about 20 minutes, if it occurs on the persistent severe pain, you should promptly seek medical attention. In addition, misoprostol not only makes the uterine smooth muscle contraction, its side effects may make the smooth muscle of the gastrointestinal tract contraction, so the symptoms of stomach pain may occur. Patients with mild symptoms are usually left untreated. Adverse reactions such as nausea, vomiting, and abdominal pain may occur after misoprostol administration, and are usually relieved gradually when the drug is discontinued. The use of this drug is contraindicated in patients with hypersensitivity to this drug or to the components of the formula, in lactating women, in patients with heart, liver and kidney diseases, and in patients with suspected ectopic pregnancy. The specific dosage and usage of the above medicines should follow the doctor’s instructions, and should not be used on their own to avoid adverse reactions.