Serious tonsil inflammation, need to identify the cause of the disease, for the cause of the treatment, there is no fast-acting special-effect drugs. Tonsillitis refers to acute tonsillitis, often caused by type B hemolytic streptococcal infection, often need to identify the cause of the disease at the same time comprehensive application of antibacterial drugs, antipyretic drugs, painkillers, clearing the throat and other drug therapy. 1. Antibacterial drug treatment: penicillin, cephalosporin (e.g. cefuroxime), macrolides (e.g. roxithromycin) and other antibacterial drugs can be selected according to the local epidemiological history; in case of suppurative tonsillitis, pus discharge can be collected with cotton swabs and sent to the laboratory for bacterial culture and drug sensitivity test, and sensitive antibiotics can be selected for the treatment through bacterial culture and drug sensitivity test. 2. Antipyretics: severe tonsillitis often have fever symptoms, body temperature higher than 38.5 ℃ can use ibuprofen antipyretic treatment, at the same time pay attention to rehydration to prevent dehydration. 3. Painkillers: severe tonsillitis pain can use non-steroidal anti-inflammatory drugs (such as celecoxib) pain treatment. 4. Heat-clearing and pharyngeal drugs: You can take the blue scutellaria oral liquid, pudilan anti-inflammatory tablets and other heat-clearing and pharyngeal drugs to assist in the treatment. When using medication, it is important to follow the doctor’s instructions, apply the medication reasonably, and do not use the medication arbitrarily, so as to avoid causing serious side effects and adverse reactions.