Mesofractionated cancer is a pathological grade of cancer with a five-year survival rate of about 30% of patients. Normally, the size and shape of cancer cells are not consistent with normal cells, and the internal structure of cancer cells is abnormal and disordered. And the size of the difference between cancer cells and normal cells can reflect the differentiation level of cancer cells and suggest the malignancy degree of cancer. Generally, cancer cells can be pathologically graded according to their differentiation level. Grade I is highly differentiated, which is less malignant; grade II is moderately differentiated, which is moderately malignant; grade III is poorly differentiated or undifferentiated, which is more malignant. Therefore, moderately differentiated cancer is a cancer of moderate malignancy, and the five-year survival rate of patients is about 30%. Patients diagnosed with intermediate differentiated cancer are recommended to actively undergo radical resection surgery to prevent the disease from continuing to deteriorate and affecting the survival period of patients.