In the process of medication abortion, the initial application of mifepristone, once every 12h, two tablets orally, a total of three times, before and after the application of mifepristone within 2h, do not have food and water intake, because mifepristone has a corresponding more obvious gastrointestinal nausea, vomiting and so on, at this time, if there is food and water intake, will induce vomiting, so that the corresponding mifepristone loses its effect. After the application of mifepristone is completed, the application of misoprostol will begin, and in about 2-3 hours after the application of misoprostol, there will be vaginal bleeding, followed by more obvious pain in the lower abdomen, and then there will be the discharge of the embryo and its appendages, and at this time, we should pay attention to observing the specific situation of the discharge and the amount of vaginal bleeding. Therefore, mifepristone should be applied first in the initial state, and the correlation between mifepristone and food and water should be noted.