Weak positive fecal occult blood can be caused by drugs, peptic ulcer and lower gastrointestinal bleeding, so the treatment needs to clarify the cause of the disease and then follow the doctor’s instructions, such as omeprazole, endoscopic hemostasis and so on. 1. Drugs: iron, bismuth and other drugs can cause fecal occult blood is weakly positive, this situation is normal, do not need special treatment, after stopping the drug, through the body’s metabolism, fecal occult blood will turn negative; 2. Peptic ulcer: mild condition can be manifested as weak positive fecal occult blood, black stool, most of the patients can stop bleeding on their own, but there are a few patients need to take omeprazole, cimetidine and other medications, or endoscopic treatment; 3. Lower gastrointestinal bleeding: for the lower gastrointestinal bleeding caused by weak positive fecal occult blood, you can follow the doctor’s advice to use aminomethylenic acid, thrombin and other drugs to stop bleeding, but also can choose to local drug spray, electrocoagulation, laser and other endoscopic treatment. In addition, other diseases can also lead to weak positive fecal occult blood, so it is recommended that such patients clarify the cause of the disease, under the guidance of the doctor to take appropriate treatment.