The feeling of tightness on the face after washing the face is considered to be related to stratum corneum defects on the face. When the stratum corneum is damaged, the epidermal thickness decreases and the feeling of tightness will appear. In addition, individuals who are allergic to certain ingredients of facial cleansers or soaps may also experience tightness after washing their faces, accompanied by obvious redness, pimples, itching and many other symptoms. Washing your face after eating certain special medications can also cause tightness, mainly represented by isotretinoin. These drugs can effectively reduce the secretion of skin sebaceous glands and reduce skin hydration after intake into the body, and similar symptoms can occur. You can apply hyaluronic acid gel or vitamin E cream directly after washing your face. The medication can increase skin hydration, reduce tightness and improve the quality of life.