Pruritus in old age can be treated by general therapy, topical medications, systemic medications, and physical therapy. Age-related pruritus is related to decreased cortical function, decreased sebum secretion, dry skin and degenerative atrophy. 1. General treatment: avoid excessive scalding, avoid scratching and other local stimuli, at the same time, do not eat stimulating food, eat more fresh fruits and vegetables. 2. Topical medication: Glycerin lotion, camphor ointment, lidocaine cream, tacrolimus ointment and other medications can be used externally to alleviate the symptoms of itching. 3. Systemic medication: generally take antihistamines, such as loratadine, cetirizine; can also be combined with sedatives, such as doxepin, amitriptyline and so on. 4. Physical therapy: phototherapy and other methods can also have a certain effect on pruritus. Elderly pruritus should be timely medical treatment, all drugs need to be used under the guidance of a professional doctor.