The clinical imaging resemblance is only a resemblance, but the diagnosis still needs to be confirmed by pathology. For those cases that are cancerous but do not look like cancer, or look like cancer but are not cancerous, as patients and family members, they must treat them calmly and rationally, and follow the doctor’s advice to obtain pathological evidence as soon as possible, so as to make a clear diagnosis. In fact, there is the phenomenon of homoeopathy and heteroepidemiology in imaging. That is, some lung lesions may be highly suspicious of lung cancer on imaging, with large masses, especially larger than 3CM, short thin burrs around the periphery, lobulated, pleural traction signs and other malignant signs, but the final pathological results suggesting tuberculosis or fungal disease or mechanized pneumonia, all occur from time to time. On the other hand, some lesions are very small, less than 50px, with relatively smooth margins, without the aforementioned malignant signs, and some may even just show partially solid ground glass shadows, strongly resembling inflammatory lesions or other benign lesions, but the final pathological diagnosis is early lung cancer. Especially in the latter case, early stage lung cancer may easily slip through the fingers of doctors and patients, thus causing lifelong regret. As patients and their families, they should strictly follow the doctor’s instructions, follow up regularly and observe dynamically. If the doctor suggests that a clear diagnosis must be made as soon as possible according to the specific patient’s condition, there is no need to hesitate and try to cooperate to complete it. For example, a 35-year-old patient was admitted to the hospital 3 years ago for pneumothorax, when a routine chest CT scan revealed a small right upper lung nodule with a length of about 13 mm, and further chest CT enhancement suggested 2/3 solid and 1/3 ground glass nodules with partial enhancement, but no obvious malignant signs were seen, considering more solid components and considering a high possibility of benign, but still not excluding the possibility of early lung cancer, and the patient had anxiety about this After examination, the patient did not find any signs of metastasis in other parts of the body, so it was suggested that direct surgery be performed to kill two birds with one stone and eliminate the problem forever. However, the patient was afraid of surgery and worried that if the lesion was benign such as chronic inflammation, it would not be worth the loss. However, in the first review in the third year, it was found to have increased by 5 mm, so the doctor strongly recommended surgery again to remove it. This reminds us that such patients who are cancerous but do not look like cancerous clinically and on imaging must be observed carefully and never hesitate to operate if there is any change in the process of close observation, combined with the patient’s psychological performance.