A large number of unreserved enemas are used to clear stool and detoxify the intestines, generally with saline contraindications are many, as follows: First, pregnant women are prohibited, because a large amount of liquid into the intestines will produce stimulation, there is the possibility of inducing premature birth, miscarriage. Second, acute abdominal disease, acute abdominal disease refers to acute pathological changes in the abdominal organs or tissues, if the gastrointestinal bleeding, macrosomia bleeding and other situations where there is perforation, the enema fluid will enter the abdominal cavity leading to serious consequences, and even myocardial infarction. Third, heart failure patients are prohibited saline enemas, because a large number of instillation of saline will cause excessive absorption of sodium ions into the blood, resulting in increased osmotic pressure of the blood, increasing the burden on the heart and aggravating the condition. Fourth, if you use soap water enema, cirrhosis patients are prohibited. Soapy water is alkaline, a large number of enemas prompt the intestinal tract to absorb ammonia, ammonia molecules through the blood circulation into the brain tissue will produce hepatic encephalopathy. Fifth, the frail, young children and the elderly are prohibited, because the intestinal flora will be destroyed, reducing the body’s immunity, fever patients should also pay attention to properly lower the solution temperature to prevent overheating.