There are many reasons for excessive urination in the middle of the night, which can be divided into physiological and pathological. When the symptoms of excessive urination in the middle of the night appear, you should immediately go to the hospital for examination, early identification, and give the corresponding treatment. I. Physiological 1. Excessive intake of water: If you urinate more each time and have no other bad performance, you can consider whether it is caused by drinking too much water. In addition, eating fruits and vegetables containing more water, such as watermelon, cucumber, celery, or food with diuretic effect, such as soy milk, green beans, winter melon, etc., will also appear more urine in the middle of the night, the symptoms can be relieved after proper control of intake; 2, urethral irritation: such as men with long foreskin or circumcision, etc., when there is urine residue, stimulate the urethra to appear more urine in the middle of the night. At this time, you need to properly treat the foreskin, such as surgery; 3, mental factors: If you are too nervous or excited during the day, drink coffee before bed, etc., can appear simple frequent urination, manifested as more urination in the middle of the night, before going to bed should avoid stimulating the nerves; 4, other: after being cold or night air conditioning temperature is too low, causing bladder contraction, some people will appear in the middle of the night urination phenomenon, need to pay attention to keep warm. Second, pathological 1, urinary tract infection: when the urinary tract infection, there will be frequent urination, urinary urgency, painful urination symptoms. You need to ensure the cleanliness of your private parts, local cleaning, and at the same time, under the guidance of a professional doctor, take antibacterial drugs such as ofloxacin and cefonicid to relieve inflammatory stimulation, thus reducing the symptoms of excessive urination in the middle of the night; 2. Reduced bladder capacity: If the daily volume of urine remains the same, while the number of urination increases, forming frequent urination, it may indicate a foreign body in the bladder, such as tumor growth and other lesions, or due to bladder tuberculosis causing bladder atrophy, which reduces the capacity of the bladder itself and results in frequent urination and excessive urination in the middle of the night. If it is a foreign body in the bladder, it can be treated by surgical removal of the lesion, and if it is bladder tuberculosis, the symptoms can be improved by drugs such as isoniazid and streptomycin; 3, drug influence: If you suffer from cardiovascular disease and take diuretics for a long time, the phenomenon of excessive urination in the middle of the night will occur, you can contact your doctor to adjust the dosage appropriately and control the primary disease; 4, prostate hyperplasia: older men are often prone to prostate hyperplasia, prostatic hyperplasia causes frequent urination, one is that the enlarged gland stimulates the bladder, and the other is that prostatic hyperplasia leads to difficulty in urination and an increase in residual urine, causing a reduction in the effective capacity of the bladder, if the symptoms are mild, drugs such as terazosin and alfuzosin can be taken for treatment, if the symptoms are severe, surgical treatment such as transurethral resection of the prostate is required; 5, kidney lesions: kidney damage, such as benign renal small artery sclerosis , kidney atrophy, etc., resulting in excessive urination in the middle of the night. As small renal artery sclerosis is closely related to hypertension, patients need to take drugs to control blood pressure and thus achieve relief from the symptoms of excessive urination in the middle of the night. Patients with renal atrophy can take ACEI class and ARB class antihypertensive drugs to lower blood pressure and glomerular intracapsular pressure, thus relieving symptoms; 6. Other: In addition to the above factors, systemic diseases, such as diabetes, uremia, etc., are also considered. Diabetic patients can take sulfonylureas and biguanides, and uremic patients can take antidiuretic drugs such as chlorosulfopropurea to relieve the symptoms of excessive urination in the middle of the night.