Causes of fever in the palms and feet include spleen qi deficiency, blood deficiency, yin deficiency of the liver and kidney (insufficient yin fluid in the liver and kidney), etc. They can be treated by using Tonifying the Middle Jiao Qi Pill, Angelica Sinensis Blood Replenishing Pill, and Zhi Bai Di Huang Pill respectively through identification of the cause of the fever. 1. Spleen governs the limbs, if the spleen qi is insufficient and the middle qi is weak, then the deficiency fire will be generated internally (the lack of yin in the body leads to the generation of fire and heat), and the symptoms of fever in the hands and feet will appear, accompanied by fatigue (mental weakness), tiredness, shortness of breath and weakness, and sweating, etc., so the Zhongzhong Yixi Pill can be used to replenish the middle qi (treating deficiency of qi by replenishing the spleen). 2. Blood deficiency and yin deficiency, yin deficiency and yang floatation is heat, which leads to five heart-heat (heat in the hearts of the hands and feet, and self-consciousness of the heart and chest), emaciation, afternoon hot flashes (a burst of heat), night sweating (abnormal sweating after falling asleep, and waking up sweating stops) and other diseases, can be used to tonify qi and blood angelica blood tonifying pills. 3. Yin deficiency of the liver and kidneys (insufficient yin in the liver and kidneys), yin not restraining yang, and external surfacing of deficient yang will lead to fever of the hands, feet and heart, accompanied by lumbago and back pain, dizziness and tinnitus, etc. Zhi Bai Di Huang Wan can be used to nourish yin and reduce fire (nourish yin essence and reduce fire). Those who have the above symptoms should consult a doctor in a timely manner and seek treatment under the guidance of a professional physician, and should not take medication on their own.