Gastrointestinal mesenchymal tumors can be treated without surgery if they are less than 2cm in size and do not have the possibility of invasive growth, but they need to be regularly reviewed, observed and followed up, and need to be standardized under the guidance of the doctor. For patients diagnosed with gastrointestinal mesenchymal stromal tumors, if they meet the indications for surgery, they need to actively undergo surgical treatment. If the treatment is not timely, it is likely to deteriorate, and with the progression of the disease, it may be life-threatening, and the best treatment time will be missed. Currently, mesenchymal tumors with a diameter of less than 2cm are considered as benign tumors. If there is no tendency of aggressive growth, conservative treatment can be adopted, but regular review is required to monitor the changes of the disease. Patients with gastrointestinal mesenchymal tumors need to undergo regular review, and the need for surgical treatment needs to be perfected with relevant examinations, and patients also need to actively cooperate with the doctor’s treatment to avoid deterioration and delay in treatment.