Severe ascariasis in adults can be treated with medication, surgical intervention and other measures. 1. Drug treatment: commonly used drugs include mebendazole, albendazole, ivermectin, piperazine citrate and other drugs. In the process of using the above drugs, if diarrhea, vomiting, rash, fever, dizziness, headache and other adverse reactions occur, it is necessary to promptly adjust the drug or stop the drug. However, it should be noted that pregnant and breastfeeding women, children under 2 years of age, drug allergies and other conditions are prohibited. 2. Surgery: In the process of drug treatment, if there is gastrointestinal obstruction or perforation, biliary ascariasis, ascaris lumbricoides appendicitis and other serious complications require surgical treatment. The above drugs need to be used under the guidance of clinicians, unauthorized use of drugs is prohibited; suspicion of ascariasis is recommended to go to the hospital in a timely manner.