Calcium Zinc Gluconate and Vitamin D₃ are generally not recommended to be taken together, if you need to combine them, you need to consult your doctor in advance. Calcium and zinc gluconate is a compound preparation, a mineral supplement, mainly used for the treatment of diseases caused by calcium and zinc deficiency, such as osteoporosis, tetany, rickets, calcium supplementation for pregnant and lactating women, menopausal women, etc. It can also be used for the treatment of pediatric growth retardation, lack of appetite, anorexia and acne. Vitamin D₃ is a fat-soluble vitamin. Vitamin D₃ promotes growth and bone calcification, promotes sound teeth, and improves the body’s absorption of calcium and phosphorus to saturate plasma calcium and plasma phosphorus levels, and can be used for the prevention and treatment of vitamin D deficiency. Calcium zinc gluconate and vitamin D₃ taken together, can promote the absorption of calcium in calcium zinc gluconate, long-term large amounts of calcium and commonly used amounts of vitamin D₃ in combination, there is a risk of hypercalcemia, so calcium zinc gluconate and vitamin D₃, if you need to be used in combination, you need to be under the guidance of a doctor. Calcium zinc gluconate and vitamin D₃ are both prohibited for patients with hypercalcemia, and drug interactions may occur when combining the two drugs together, which need to be followed to minimize the risk of drug use.