Perianal itching and wetness may be caused by perianal eczema, hemorrhoids, anal papillae hypertrophy and other diseases, the causes are different, the treatment is also different. 1. Perianal eczema: perianal eczema is a perianal skin peripheral skin of a perverse reaction skin disease, is a type of eczema, perianal eczema patients can have perianal itching and wet symptoms, treatment can be used in aluminum acetate wet compresses, zinc oxide ointment topical application of the affected area, but also oral loratadine and other medications for treatment. 2. Hemorrhoids: hemorrhoids is a disease of congested and enlarged veins in the anal canal or lower rectum, patients can have perianal itching and wet symptoms, but also with blood in the stool, pain in defecation, hemorrhoidal prolapse and other symptoms, the treatment should first improve the symptoms of constipation, in addition to the use of hemorrhoidal ointment coated with the affected area, but also through surgery for treatment. 3. Anal papillae hypertrophy: anal papillae hypertrophy, also known as anal papilloma or papillary fibroma, is a kind of proliferative inflammatory changes in the disease, the patient can appear perianal itching moist symptoms, treatment should improve constipation, can use 1:5000 potassium permanganate warm water sitz bath clean local, but also through the surgical excision of anal papillae to treat. In addition to the above diseases, other diseases may also lead to perianal itching and moist symptoms, if this symptom persists without relief, please consult a doctor in time to clarify the cause of the disease and give treatment to avoid delaying the condition. Drugs should be applied under the guidance of a doctor.