Detoxification in Chinese medicine generally refers to the relief of heat and toxicity, there is no best drug for detoxification, but drugs such as clearing heat and detoxification granules, oxalic detoxification tablets, honeysuckle granules and so on can play a role in detoxification. Heat-clearing and detoxifying granules belong to Chinese patent medicine, which is composed of Da Qing Ye, Lian Qiao and Zhi Mu, etc. It has the effect of clearing heat and detoxifying toxins, nourishing yin and generating fluids, and catharticizing fire. It can be used to treat wind-heat type cold, mumps and other diseases. Niu Huang Antidote Tablet belongs to Chinese patent medicine, which is composed of artificial niu yu huang, xiong huang, gypsum, etc. It has the effect of clearing heat and detoxifying toxins. It can be used to treat diseases such as internal heat, sore throat, swollen gums and so on. Honeysuckle Granules belongs to Chinese patent medicine, which is composed of honeysuckle and Lonicera japonica. It has the efficacy of clearing heat and removing toxins. It can be used to treat fever and thirst, sore throat, heat boils and ulcers and other diseases. The adverse reactions and disabling of the above drugs are not clear. Patients can choose suitable drugs with detoxification effect under doctor’s guidance.