Parkinson’s disease is due to degenerative lesions in the central nervous system of the brain, resulting in limb movement disorders, and with the passage of time, the symptoms gradually aggravate, to the patient’s physical and mental health, work and life bring great distress, in order to improve the patient’s symptoms, improve the quality of life. In order to improve the patient’s symptoms and improve the quality of life, patients need to be detected and treated early, with a good prognosis. In the treatment, once diagnosed with Parkinson’s disease, patients need to take long-term medication, now the main drugs in the clinic are Meidoba, resting, Kodan, Senforo, Antan, Tysudan, amantadine, Darin Fo, Ropinirole, Reserpine, etc. A variety of drugs, each drug has its own role, for example, the Meidoba, resting, is from the outside world to supplement dopamine neurotransmitter, the Meidoba fast-acting, resting to delay the time of the long, Kodan must be with the Meidoba, resting. Longer, Cotan must be taken with Methyldopa to promote more dopamine neurotransmitter and receptor binding, and Antan to improve the symptoms of Parkinson’s disease by inhibiting the degree of excitation of acetylcholine, and so on. However, the drug has a “honeymoon period” characteristics, generally about 5 years of time, the effectiveness of the drug will gradually decrease, so in order to extend the time of the drug as well as let the drug effect better play, patients and their families should know more about some of the precautions of taking drugs. 1, Parkinson’s drugs must be taken from a small dose: according to the situation gradually increase the amount to do. 2, fasting: the best time for 30 minutes before meals, followed by 1 hour before meals or 2 hours after meals. Because this kind of medicine with food will reduce the absorption rate. 3, prohibit acetylcholine: because Parkinson’s disease is due to hyperfunction of the acetylcholine system resulting in increased muscle tone, decreased movement, muscle tremor, so should pay attention to the intake of acetylcholine drugs. 4, prohibit calcium antagonists: for example, nifedipine a class of antihypertensive drugs. The antagonism between drugs reduces the effectiveness of drugs. 5, prohibit gastrointestinal power drugs: such as morphine. Because gastric power drugs have blocked the role of dopamine, promote gastric emptying, reduce the absorption rate. 6, prohibit vitamin B6: because vitamin B6 is the coenzyme of dopamine dehydroxylase, improve the activity will promote the formation of dopamine in the brain outside the drug, reduce the amount of access to the central nervous system, thus reducing the effectiveness of the drug. 7, glaucoma patients should be used with caution: because dopamine is a drug that can raise blood pressure, there is a certain effect on intraocular pressure, so you need to pay attention to changes in intraocular pressure during the drug. 8, the time to take medicine and meal time must be separated: the time to intake of high-fat and high-protein food must be separated from the time to take medicine, thought that high-protein food produces a large number of amino acids, amino acids can impede the absorption of levodopa in the intestinal tract, so that its efficacy is reduced. You can’t take the medicine immediately after eating, you can choose to take the medicine one hour before the meal or two hours after the meal.