Coronaviruses are a large group of viruses that are known to cause disease, with patients presenting with clinical symptoms ranging from the common cold to severe lung infections, such as the novel coronavirus discovered in Wuhan, as well as Middle East Respiratory Syndrome (MERS) and Severe Acute Respiratory Syndrome (SARS). Coughing without fever is a possible manifestation of novel coronavirus infection. Novel coronavirus is often characterized by fever, malaise, dry cough, etc., and a few patients are accompanied by upper respiratory and gastrointestinal symptoms such as nasal congestion, runny nose and diarrhea. It is worth noting that severe and critically ill patients may have low to moderate fever during the course of the disease, or even no obvious fever. Some patients also only show low fever, slight fatigue, and so on, and no pneumonia manifestations, mostly in 1 week after the recovery. A few infected patients have no obvious clinical symptoms and only test positive. The diagnosis can be confirmed when patients test positive for novel coronavirus nucleic acids by real-time fluorescence RT-PCR of respiratory specimens or blood specimens, or by viral gene sequencing of respiratory specimens or blood specimens, which are highly homologous to known novel coronaviruses. The presence of a cough without fever symptoms may be a manifestation of Middle East Respiratory Syndrome. Typical manifestations of Middle East respiratory syndrome often include symptoms such as fever, cough and shortness of breath, and pneumonia manifestations are often found on examination, as well as gastrointestinal symptoms such as diarrhea. Some patients infected with the virus do not develop symptoms, but are detected with the presence of Middle East respiratory syndrome coronavirus in follow-up studies of close contacts of infected cases. In addition, cough without fever can be seen in infectious diseases such as bronchitis, bronchiolitis, and pneumonia, as well as non-infectious diseases such as bronchial asthma and bronchiectasis. Patients need to improve the routine blood test, as well as lung function, exhaled nitric oxide test, and improve the CT examination of the lungs, in order to clarify the diagnosis. In conclusion, only cough without fever symptoms may be a manifestation of coronavirus, but not absolute, patients do not need to worry too much, can be clearly diagnosed and then treated. Source: Dr. Yurai Reference: NHSC “Guidelines for Public Protection against Pneumonia due to Novel Coronavirus Infection” NHSC “Q&A on Middle East Respiratory Syndrome”.