Often stay up late eye pain is usually due to visual fatigue, dry eye, keratitis and other reasons, can be used conservative treatment, drug treatment, surgical treatment and other methods of treatment. 1. Visual fatigue: visual fatigue is usually caused by insufficient light, uneven distribution of light sources, neurasthenia and other reasons, there will be eye pain, blurred vision, dry eyes and other symptoms, you can shorten the time of eye use in daily life, eat more food rich in vitamins A, B and so on. 2. Dry eye: dry eye is usually due to insufficient tear secretion, insufficient secretion of the oil layer and other reasons, there will be burning sensation, dryness, itchy eyes and other symptoms, you can use topical artificial tears such as sodium vitrate eye drops to relieve symptoms. 3. Keratitis: Keratitis is usually caused by long-term use of contact lenses, eye trauma and other reasons, there will be eye pain, photophobia and other symptoms, you can use topical antibiotic eye drops such as ofloxacin, tobramycin eye drops. It is recommended that patients go to the hospital in time for examination and treatment under the guidance of the doctor.