The presence of vague pain in the breast but no lump is considered to be mastocytosis. Breast enlargement, also known as lobular hyperplasia, is a benign disease with a high incidence in women around 40 years of age and is usually associated with hormonal disorders in the body. Before the onset of menstruation, the body’s estrogen level rises, which can lead to hyperplasia-like changes in the glands and alveoli of the breast. The repeated occurrence of hyperplasia can lead to pain in both breasts, sometimes in the form of vague pain, sometimes like pins and needles, and sometimes very obvious pain, including when pressing with the hand, there may be pain, but during physical examination there may be no lumps, just some sand-like The sensation. The pain may be relieved on its own when the estrogen level recedes to normal after the menstrual period, and you can come to the hospital for an ultrasound examination of the breast to further clarify the diagnosis. If the diagnosis is clear that it is caused by breast enlargement, you need to take oral Chinese medicine for symptomatic treatment, such as Zhuangyao pill, breast fetish elimination, red gold anti-knot capsule and so on. If the pain is very obvious, you can also consider taking oral painkillers for symptomatic treatment, such as fenbid or celecoxib.