The core pathogenesis of herpes zoster (snake pox) is the direct damage to the nerves caused by the virus and the secondary damage caused by the autoimmune cells attacking the affected nerves. When the virus is not latent in the nerve, the virus and the nerve are mixed together, just as the enemy in disguise is mixed with the common people, and the two cannot be distinguished from each other, so that their own defense forces do not attack and are left in peace. When the body’s resistance decreases, the enemy tears off the camouflage and causes chaos in the area, and the defense forces find the situation and attack the area, the immune cells attack the virus and the nerves are involved, that is, when eliminating the enemy, even the people are killed and injured together, making the damage further aggravated. This secondary immune inflammatory response can be much more severe and sometimes last for a long time. In simple terms, these nerves are inflamed and damaged. The neuritis pain is often described by the patient as the affected body feeling like it is on fire, being pricked by pins and needles, jumping around, being cut by a knife, etc. Sometimes it is so intense that the patient has trouble sleeping through the night, and in some elderly patients it doesn’t take long for the body to be quickly crushed. Because nerve damage is hidden deep down, it is mostly not taken seriously, but in fact this is the key to the pain caused by shingles (serpentine) that torments patients for so long. Therefore, stopping and reducing nerve damage and promoting recovery of damaged nerves is a central part of the treatment of shingles (serpentine). The nerve damage sometimes worsens with time, so herpes zoster neuralgia should be treated early and should not be delayed. Severe pain also causes a series of chain reactions: local sympathetic hyperexcitability leads to local vasoconstriction and poor circulation at the lesion site, which in turn aggravates the nerve damage and makes the pain worse. and cost.