Spike-and-slow waves are pathological waveforms caused by abnormal discharge of neurons in the brain during EEG examination. If the diagnosis of epilepsy is confirmed, the patient should be given oral medication, often choosing carbamazepine, phenytoin sodium, sodium valproate and other drugs. If the patient’s spiky waves are caused by traumatic brain injury or intracranial infectious disease, active treatment of the onset of the disease should be accompanied by the administration of drugs to control the epilepsy caused by abnormal neuronal discharge in the brain. After the onset of spike-and-slow waves, the patient should also undergo EEG review after taking oral medication to check the reduction of spike-and-slow waves. Patients are also advised to have regular liver and kidney function tests, as most antiepileptic drugs have some damage to liver and kidney function.