How to diagnose gallbladder wall fibrosis

When the gallbladder wall is inflamed and fibrotic, the gallbladder is contracted, which is known as chronic non-stony cholecystitis. Infection and obstruction are caused by the presence of stones in the gallbladder or in the neck of the gallbladder. Such a condition may be related to the problems of cholecystic duct syndrome, inflammatory gallbladder stones, colonic hepatic flexural adhesion syndrome, and also to post cholecystectomy syndrome, ascariasis of the gallbladder, acute cholecystitis caused by stone cholecystitis carcinoid tumor, and other causes of the disease, to see if there is an abnormal fever. How should the diagnosis be made? Stones in the gallbladder generally do not produce symptoms of biliary colic, called resting stones, and may have symptoms of indigestion such as hidden pain in the right upper abdomen, acid reflux, belching, abdominal distension, etc., which are obvious after ingesting fatty food, and may have symptoms of acute cholecystitis if accompanied by infection. The stones in the gallbladder duct may manifest as biliary colic, with sudden onset of persistent pain in the right upper abdomen, worsening in paroxysms, and spreading to the back of the shoulder, accompanied by nausea and vomiting. See acute and chronic cholecystitis for more details on consultation points. Intracholangiocystic stones may have no positive signs, but in a few cases, the gallbladder may be palpable if the stones are too large. In the case of intracholangiocystic ductal stones, right upper abdominal pressure pain, Murphy’s sign is positive, enlarged gallbladder can be palpated in the right upper abdomen with pressure pain, and in case of gallbladder perforation, signs of acute peritonitis such as whole abdominal pressure pain, rebound pain and muscle tension can be present. Some patients may develop jaundice. In case of gallbladder perforation, subseptal free gas can be seen on abdominal plain film.