Serum prealbumin 88mg/L, which is below the normal reference range, may be related to liver insufficiency and protein malnutrition. Serum prealbumin is a transportation protein in blood, and its main physiological function is to bind and transport vitamin A and thyroxine. Clinically, it is often used as an indicator to reflect liver function damage and various malnutrition. Normal human serum prealbumin reference value range is 240~350mg/L, so serum prealbumin 88mg/L is low. When serum prealbumin is 50~100mg/L, it belongs to moderate deficiency, which may be related to severe hepatitis, acute hepatitis, hepatocellular carcinoma, obstructive jaundice and other diseases, and may also be related to malnutrition. To summarize, when there is a decrease in serum prealbumin, please go to the hospital in time and clarify the cause of the disease under the guidance of the doctor, so that targeted treatment can be carried out.