Gastric cancer is the most common malignant tumor of digestive tract. In China, there are obvious geographical differences in the incidence of gastric cancer, which is significantly higher in northwest and eastern coastal regions than in southern regions. 40-60 years old is the age of prevalence, and the ratio of male to female incidence is 2:1. According to statistics, the incidence of stomach cancer in the family members of stomach cancer patients is four times higher than that of normal people. In addition, the incidence rate of A-type blood is higher than that of O-type, suggesting that the occurrence of gastric cancer is also related to genetic factors. The cells of origin of gastric cancer are stem cells in the neck of the gastric gland. In addition, intestinal epithelial metaplasia is also one of the cytological bases of gastric carcinogenesis. The prognosis of gastric cancer is related to the pathological stage, site, tissue type, biological behavior and therapeutic measures of gastric cancer. At present, the most effective treatment for gastric cancer is still surgery. In China, the 5-year survival rate after surgery is about 40% due to the low number of gastric cancers detected at early stage and the lack of advanced surgical techniques. Japan is a country with a high incidence of gastric cancer, which pays much attention to medical checkups and has a high rate of early gastric cancer and a 5-year survival rate of about 65% after surgery. It can be seen that regular gastroscopy is important for early detection of gastric cancer. Chemotherapy is the main treatment for gastric cancer other than surgery. Before and after surgery, adjuvant chemotherapy can be used to improve the surgical resection rate, reduce the recurrence rate and improve the survival rate, and for patients who cannot be operated, recurred after radical surgery or explored, chemotherapy is the main method of comprehensive treatment.