High C-reactive protein, nausea, vomiting and fever are considered to be related to acute gastroenteritis, acute pancreatitis, acute cholecystitis and acute appendicitis. Generally, medication or surgery is needed. 1. Acute gastroenteritis: Acute gastroenteritis caused by improper diet or irregular life will cause elevated C-reactive protein, fever, nausea, vomiting, diarrhea and other symptoms. Generally, acid-suppressing and anti-inflammatory drugs such as omeprazole and levofloxacin should be given. 2. Acute pancreatitis: the main symptom is sudden epigastric pain, accompanied by fever, nausea, vomiting, abdominal distension and other symptoms, at this time the C-reactive protein will also be elevated. The main symptom is a sudden pain in the upper abdomen, accompanied by fever, nausea, vomiting, abdominal distension and other symptoms. 3. Acute cholecystitis: Typical symptoms are sudden onset of abdominal pain, nausea, vomiting, fever and other symptoms. Generally need to apply antibiotics and antispasmodic painkillers, such as ceftazidime, belladonna tablets, ursodeoxycholic acid tablets. Or surgical treatment. 4. Acute appendicitis: generally there will be pain in the lower right abdomen, and accompanied by nausea, vomiting, fever, C-reactive protein elevation, etc.; generally the application of anti-infective drugs and surgical treatment. The above drugs are not self-medication, should be used under the guidance of a doctor, if the above symptoms, it is recommended to go to the hospital, under the guidance of the doctor early formal treatment.