Pancreatic kininogenase enteric-coated tablets can be taken orally on an empty stomach before meals, there is no specific time, a few minutes or a few hours before meals will not have a significant gap, pay attention to the three times a day, to 8 hours of medication spacing is good. Pancreatic kininogenase enteric-coated tablets are vasodilators, with the effect of improving microcirculation. It is mainly used for microcirculation disorders, such as diabetes-induced nephropathy, peripheral neuropathy, retinopathy, fundopathy and ischemic cerebrovascular disease. Because it orally does not stimulate the gastric mucosa, will not cause damage to the gastric mucosa, and enterosolvent, mainly absorbed from the intestines, fasting is more conducive to rapid entry into the intestinal tract, the general fasting into the intestinal tract for 4 hours plasma concentration peak, half-life of 7 hours, mainly through the renal excretion. So as long as the oral fasting can be, do not need to be specific a few hours before the meal time. After taking the drug if the rash, skin itching and other allergic phenomena and stomach upset and tiredness and other feelings, do not be nervous, usually disappear after stopping the drug. This product can not be used with protease inhibitors can not be used at the same time, this product and angiotensin converting enzyme inhibitors (ACEI) have a synergistic effect, if used at the same time will change the original effect of these drugs. It is contraindicated in the acute phase of cerebral hemorrhage and other bleeding disorders. There are individual differences in the use of medication, patients should consult a doctor for diagnosis before use, to determine the condition and then strictly follow the doctor’s instructions to use the drug, do not blindly use the drug in private to avoid damage.