Upper heat and lower cold is a syndrome of Chinese medicine, the most effective treatment method can not be generalized, need to be based on the identification of Chinese medicine practitioners to choose the appropriate method, nowadays the clinical usually use traditional Chinese medicine soup for treatment, commonly used formulas such as Jiaotai pill, appendicia laxative cardiac soup and so on. Upper body heat and lower body cold refers to the upper part of the body shows a series of hot symptoms, such as frequent vomiting, abdominal pain, like warmth, like warmth; while the lower part of the body shows a series of cold and hot symptoms, such as diarrhea, stools are not shaped, and so on. Because the patient’s manifestation of cold and heat is mixed, the treatment is more complicated and needs to be recognized and treated by experienced Chinese medicine practitioners, and can be treated with Chinese medicine soup. For patients with upper heat and lower cold, the treatment needs to “lead the fire back to the source” (inhibit the fire of the kidneys from rising), which can be treated with Jiaotai Pills, in which Huanglian subdues the fire to make it go downward, and Cinnamon leads the fire back to the source, and the combination of these two medicines achieves the therapeutic effect. The upper heat and lower cold can also be treated with Pseudostemonium laxative heart soup, which can clear the upper heat and warm the lower cold to achieve the therapeutic effect. The specific prescription needs to be identified by a traditional Chinese medicine practitioner, patients should not use their own medicine.