Sore legs at night may be caused by neuropathy, lumbar disc herniation and calcium deficiency. 1. Neuropathy: If the nerves are damaged, it may lead to loss of sensation or muscle weakness, accompanied by atrophy, which may cause the symptoms of sore legs at night. 2. Lumbar disc herniation: when various parts of the lumbar intervertebral disc appear different degrees of degenerative changes, it may cause lumbar intervertebral disc herniation, so that the intervertebral disc’s fibrous ring rupture, compression of the leg-related nerves, there may be a leg soreness of the night can’t sleep situation. 3. Calcium deficiency: If you have been eating irregularly for a long time, often picking and favoring food, it may lead to a lack of calcium in the body, which can cause sore legs at night when you sleep and can’t sleep. Sore legs can not sleep at night does not rule out other causes, it is recommended to go to the hospital as soon as possible to do a checkup, clear causes, and active treatment.