There are many kinds of gallbladder diseases, such as acute simple cholecystitis, acute purulent cholecystitis, acute gallbladder perforation, gallbladder stones, gallbladder adenomyosis, gallbladder malignant tumor and so on. Therefore, it is necessary to go to the hospital to improve the corresponding examination to clarify what kind of disease the gallbladder has, such as blood routine, liver function, five items of hepatitis B, four items of infection and tumor markers such as alpha-fetoprotein, carcinoembryonic antigen, glycogen antigen 19-9, glycogen antigen 12-5, etc. Sometimes it is also necessary to check the abdominal ultrasound or abdominal CT, abdominal MRI, etc. If infection is considered to be the cause, antibiotics should be actively administered and the gallbladder should be surgically removed. If it is considered to be caused by malignant lesions, radical resection of the tumor is needed, and later chemotherapy and targeted drug therapy may be required.