A 0.5cm wide-based bulge in the descending colon may be due to inflammatory polyps, colon tumors, etc. A biopsy is needed to clarify the nature of the bulge, which can be resected by surgical methods, and treated with chemotherapy and radiotherapy if necessary. If the patient has a polyp in the descending colon, after biopsy, if it is caused by inflammatory factors, it may be manifested as a 0.5cm broad-based bulge, which indicates that the condition is relatively mild, and can be treated through enteroscopic resection and other methods. In addition, if the patient has a tumor in the descending colon, it may also be manifested as a broad-based bulge, indicating that the condition is more serious, and surgery is required at this time. After surgery, depending on the degree of development of the condition, treatment may be required through radiotherapy or chemotherapy, and so on. When the patient has 0.5cm broad-based bulge in the descending colon, it is recommended to go to the hospital in time, to clarify the cause of the disease under the guidance of the doctor, and to carry out reasonable treatment.