Beale’s respiration is a pathological respiration, also known as intermittent respiration, which is clinically manifested by the interruption of breathing after several regular breaths, followed by regular breathing after a certain period of time. It is most often seen in end-stage disease respiratory center failure and severe traumatic brain injury that endangers the respiratory center, which is a sign of a weakened respiratory center. The normal respiratory rhythm is maintained by the respiratory center, which receives signals of hypoxia in the peripheral blood, such as carbon dioxide, and the elevated carbon dioxide in the blood will stimulate the respiratory center to excite it to maintain the respiratory rhythm. When the respiratory center is severely impaired, the respiratory center is no longer sensitive to the signal of blood hypoxia manifested as apnea, which leads to severe hypoxia after a certain period of time, and it is only through the vascular reflex and stimulation of the respiratory center that the respiratory action is resumed. Therefore, the appearance of Beale’s respiration and respiratory center dysfunction are closely related, seen in the end stage of disease respiratory center failure or severe brain injury, etc.