The condition of hard lumps on the sole of the feet may be caused by callus, corns, plantar warts, etc. Patients can improve their condition through general treatment, medication, surgery and physical therapy. 1. Callus: patients should try to avoid friction and pressure, you can use hot water to soak the affected area, and then polish the affected area with a foot grinding stone. Patients can use sulfur salicylic acid ointment, Vitamin A acid ointment and other medicines to apply to the affected area as prescribed by the doctor, or through liquid nitrogen freezing, carbon dioxide laser and other ways of physical therapy. 2. Corns: patients can follow the doctor’s instructions to use corns cream, salicylic acid ointment, 40% urea ointment and other drugs for local treatment, or the use of cryotherapy, laser therapy and other ways of physical therapy. For the conservative treatment effect is not obvious and more serious corns, can be through the way of surgery to dig out the corns. 3. metatarsal warts: patients should maintain foot hygiene and cleanliness, try to choose shoes with soft soles to reduce or eliminate the pressure and pain when walking, avoid walking barefoot. You can use salicylic acid, 5% fluorouracil ointment, 5% imiquimod ointment and other medications under the guidance of a doctor, or physical therapy through laser, electrocoagulation, liquid nitrogen cryotherapy. It is recommended that patients strictly follow the doctor’s instructions for medication, actively cooperate with the doctor’s treatment, develop good personal life and hygiene habits in daily life, and avoid intense scratching and so on.