A 24-hour urine protein of 0.4g is usually not serious. A normal person’s 24-hour urine protein quantification is less than 0.15g, and more than 0.15g is called proteinuria.0.4g urine protein belongs to a small amount of proteinuria, so it is usually not serious. There are physiologic and pathologic reasons for small amounts of proteinuria, as follows: 1. Physiological reasons: healthy people will have a small amount of proteinuria after strenuous exercise or when standing up. Sometimes high fever or cold weather can also cause proteinuria. A small amount of proteinuria can also occur during times of stress. These common conditions are physiological reasons, not due to renal disease proteinuria. 2. Pathological causes: Pathological causes are small amounts of proteinuria caused by primary or secondary kidney disease. Kidney damage causes protein to be filtered from the kidneys and excreted from the body. Oral valsartan and Benadryl can be taken as prescribed by the doctor, and regular rechecks can be performed. Patients with abnormal 24-hour urine protein are advised to consult a hospital in time, and under the guidance of a physician, diagnose the disease according to the symptoms and signs, tests and past medical history, and give appropriate treatment plans.