A thickening of the bowel wall is not necessarily an early stage of cancer. There are two main types of causes of bowel wall thickening: neoplastic and non-neoplastic. Neoplastic causes include benign smooth muscle tumors or malignant neuroendocrine tumors, while non-neoplastic causes include inflammatory lesions or Crohn’s disease. However, bowel cancer can cause thickening of the bowel wall. If the above situation occurs, it is recommended to go to the hospital for standardized examination in time, and it is recommended to combine the specific symptoms and signs with enteroscopy under the guidance of the doctor to make a clear diagnosis. If the thickening of the intestinal wall is caused by enteritis, it is usually a uniform and diffuse thickening. On the other hand, bowel wall thickening due to tumor is mostly localized and uneven. Then according to the different conditions, take targeted treatment.