Usually there are several factors for the swelling of the hands in the afternoon: 1. The most common factor is cervical spondylosis or thoracic outlet increase cooperation, which is easy to compress the veins, resulting in obstruction of venous return in the upper extremities, and there will be swelling of the hands in the afternoon. 2. In patients with renal insufficiency and cardiac insufficiency, there will be insufficient blood transportation in the afternoon, and the body cannot excrete water out of the body adequately, resulting in a certain amount of sodium and water retention. 3. The swelling of the hands will occur in the afternoon. 3, in the peripheral neuritis, such as past history of diabetes patients, there will be peripheral neuritis in the hands in the afternoon, resulting in hand swelling. 4, in the rheumatic osteoarthropathies, such as rheumatoid arthritis, rheumatoid arthritis, as well as gouty diseases will be in the afternoon when the swelling of the hands.