In general, hypertension drugs are divided into six categories, hypertension drugs include beta-blockers, diuretics, calcium antagonists, alpha-blockers, ARBs, ACEIs. Different types of drugs, contraindications are also different, including some of the diseases of liver and renal insufficiency with caution, some patients with caution, and so on. 1. Diuretics: thiazides such as hydrochlorothiazide, used with caution in patients with dyslipidemia and dysglycemia, and contraindicated in patients with gout. Potassium-preserving diuretics, such as amphotericin, spironolactone, can not be combined with ARB, ACEI, and renal insufficiency is prohibited. Indapamide, with vasodilator and diuretic effects, can effectively lower blood pressure and less likely to cause hypotension. 2. β-blockers: such as bisoprolol, etc. It is prohibited in patients with chronic obstructive pulmonary disease, asthma, second and third degree atrioventricular block, hyperlipidemia, peripheral vascular disease and acute renal failure. 3. Calcium antagonists: atrioventricular block, heart failure patients are forbidden. 4. ACEI: prohibited in patients with hyperkalemia, bilateral renal artery stenosis, renal failure, pregnancy, creatinine greater than 3mg/dL or 265umol/L. 5.ARB: It is the replacement drug when adverse reaction occurs when taking ACEI, and it has its own efficacy characteristics. 6. α-blockers: such as phentolamine, etc., are prohibited in patients with postural hypotension. Due to individual differences, the use of hypertension drugs need to be taken under the guidance of a doctor, prohibited from stopping the drug or arbitrarily increasing or decreasing the dose to take.