Bivalent, or bivalent HPV vaccine, which requires a total of 3 shots. Generally, after the first shot, the second shot can be given at an interval of 1 month and the third shot at an interval of 6 months. The bivalent HPV vaccine includes bivalent human papillomavirus adsorbed vaccine and bivalent human papillomavirus vaccine (E. coli), which can be used to prevent cervical cancer and other diseases caused by high-risk human papillomavirus (HPV) types 16 and 18. The vaccine requires a total of three injections, and is generally recommended to be administered according to the principle of “0-1-6”, i.e., the date of the first injection is 0, and then the second and third injections can be administered at intervals of 1 and 6 months. It should be noted that some people may have fever, fatigue, headache, nausea, vomiting, diarrhea, pain, swelling, itching, erythema and other adverse reactions at the injection site after receiving this vaccine. Therefore, those who have serious allergic reactions to any of the active ingredients or excipients should be prohibited from receiving the vaccine, and those who have serious allergic reactions after receiving the vaccine should not receive the vaccine again.