The absence of follicles is mostly due to ovulation disorders, endocrine hormone disorders, ovarian diseases and other factors. 1. Ovulation disorder: if there is polycystic ovary syndrome, hyperprolactinemia and other diseases will cause ovulation disorder, which will lead to the phenomenon of no dominant follicles. 2. Endocrine disorders: follicle development process is regulated by a variety of endocrine hormones, if due to different reasons lead to the hypothalamus, pituitary gland, ovaries and other endocrine organs hormone imbalance, will lead to no ovulation. 3. Ovarian disease: If ovarian disease or premature ovarian failure is caused by ovarian tumor or medication, it will affect the ovarian function and no follicle will appear. If the patient does not ovulate, it is recommended to consult a medical professional in time.