The brain is the commanding officer of the human body and governs all the life activities of the body. Of course, the normal performance of brain function is also inseparable from the peripheral support, such as the cranium to support and protect the brain from external aggression, providing a safe, closed, stable intracranial operating environment. In reality, however, there are a variety of risk factors that may cause damage to the skull, such as car accidents, such as traffic accidents, such as brain surgery due to craniocerebral disease and so on, may result in cranial defects. This will expose the brain to external dangers, destabilize the stable intracranial environment, cause blood circulation and cerebrospinal fluid circulation disorders, and affect the operation of various neurological functions, which is very harmful to the organism and sometimes even fatal. Therefore, once a cranial defect occurs, cranial bone repair surgery needs to be performed in a timely manner. Cranial bone repair is now one of the more common routine surgery in neurosurgery, and there is no very high technical difficulty at the surgical level. However, there is also a major factor that restricts the effectiveness of the surgery, which is the application of the repair material. Currently, the new PEEK material is used in clinical cranial bone repair. We are using this advanced new material, polyether ether ketone peek material, which can be three-dimensional molding, has a high degree of biocompatibility, insulation, strength, hardness, elasticity, etc. are comparable to the autologous skull, is an excellent cranial bone repair material.