Spots on the nose may be freckles, chloasma and seborrheic keratosis, which are mainly related to heredity, hormone level change, ultraviolet radiation and immunity abnormality. 1. Freckles: autosomal dominant inheritance is the main factor of freckles, while sun exposure and ultraviolet irradiation can also induce freckles. Freckles are round, ovoid or irregular in shape, with the color ranging from light brown to dark brown. The number of freckles varies, and they can be manifested as spots on the nose. 2. Chloasma: spots on nose may be chloasma, the cause of which is not clear yet, which may be related to genetic factors, ultraviolet irradiation, changes in the level of sex hormones and other factors leading to impaired metabolism of melanin in the skin and impaired epidermal barrier function. In addition, chloasma can be induced by long-term application of certain drugs or cosmetics and liver diseases. 3. Seborrheic keratosis: mainly seen in adults over 40 years old, it can cause spots on the nose of some people, with clear boundaries and rough surface, and individual patients are accompanied by itching or pain. The appearance of seborrheic keratosis is related to skin aging, genetic factors, etc., while ultraviolet radiation, viral infections, etc. can induce seborrheic keratosis. It is recommended that people with spots on the nose should seek medical examination in order to clarify the cause of the disease and then follow the doctor’s instructions for treatment. Pay attention to daily skin care and avoid direct exposure to ultraviolet rays.