Cerebral stroke is also known as stroke, in which acute ischemic stroke (AIS-LVO) caused by occlusion of large arteries is a serious clinical emergency with poor prognosis and high mortality rate, which is an ischemic cerebrovascular disease caused by occlusion of arteries supplying blood to the brain (carotid and vertebral arteries) and insufficient cerebral blood supply as a result of an acute thrombus in the cerebral artery. The key to treatment is to open the occluded vessels at an early stage to save the ischemic semi-dark band.The causes of AIS-LVO include artery-to-artery embolism, cardiogenic embolism, and cryptogenic stroke, etc., of which the most common cause in our country is the artery-to-artery embolism caused by dislodgment of embolus due to atherosclerosis.The patients with AIS-LVO have a variety of clinical manifestations, the most common of which include crooked angle of the mouth, gaze, hemiplegia, hemianopsia, and hemianopsia, aphasia, sensory deficits, and often impaired consciousness.Diagnostic tools for AIS-LVO include head CT arteriography (CTA), magnetic resonance arteriography (MRA), and cerebral arteriography (DSA). CTA is the most common test used in the emergency room to identify AIS-LVO, and it is recommended that all patients with suspected acute ischemic stroke should have a CTA completed.Treatment of AIS-LVO includes intravenous thrombolysis or endovascular interventional mechanical thrombolysis.The results of the 2015 “Big Five Clinical Study” of mechanical thrombolysis confirmed that the treatment of AIS-LVO is not effective in patients with acute ischemic stroke, but rather in patients with acute ischemic stroke. The results of the 2015 “Big 5 Clinical Study” of mechanical thrombolysis confirmed the superiority of endovascular intervention over pharmacologic therapy in patients with AIS-LVO. Endovascular thrombolysis can open blood vessels early, as in the case pictured here, and can be truly life-saving.