Chromosome problems can give birth to normal children with the specific type of abnormality, general structural abnormalities themselves conceived the probability of giving birth to normal children is relatively small, the number of abnormalities generally can not give birth to normal children. 1. structural abnormalities: chromosomal structural abnormalities will, to a certain extent, cause an increase in the probability of miscarriage, stillbirth and other risks, but there will be a part of the population to give birth to a normal child, but the probability is relatively small. 2. Abnormal number: If there is an abnormal number of chromosomes, for example, 45X, less than one X chromosome, this kind of situation usually can not realize natural conception, naturally will not give birth to normal children. It is recommended that both parties do a detailed prenatal examination before getting pregnant, and intervene in time when problems are found, so as to avoid causing other serious problems.